Outcome of Kidney Transplants in Recipients of Young Donors: A NAPRTCS Data Analysis

Publication Type
Journal Article
Year of Publication
2011
Authors
Moudgil, A; Martz, K; Stablein, D; Puliyanda, D
Secondary
Pediatr Transplant
Volume
15
Start Page
167
Pagination
167-171
Date Published
03/2011
Keywords
Glomerular filtration rate; Graft Survival; Kaplan-Meier; Kidney Function Tests; kidney transplantation; Living Donors; Marginal donors; Middle Aged; pediatrics; Postoperative Care; Registries
Abstract
{NAPRTCS data were analyzed to assess outcome of TX recipients from YDs (<5yr) in comparison with IDs (6-35yr) and ODs (36-55yr). Of 9854 TX in NAPRTCS (1987-2003), 469 were YD. Patient survival (PS) and graft survival (GS) were compared between DD TX after 1995; 81YD, 1324 ID, and 429 OD and eGFR were compared among functioning grafts (YD 31, ID 439, OD 174) at threeyr. PS was comparable in all groups; GS at one, two, and threeyr in TX of YD (91.1%, 83.8%, 79.7%), ID (93.5%, 89.7%, 83.6%), and OD (92.2%, 87.2%, 82.4%) was comparable. The eGFR in YD was comparable to ID but better than OD (86.5 vs. 79.7 vs. 67.2mL/min/1.73m(2), p 0.139 and <0.0003). Primary graft non-function was more frequent in TX from YD than ID and OD (3.7% vs. 0.3 and 0.7%